The role of cell adhesion molecules in recurrent implantation failure
نویسندگان
چکیده
منابع مشابه
I-24: The Role of Interleukins, Integrins and Other Proteins in Recurrent Implantation Failure
Embryo implantation represents the most critical step of the reproductive process in many species. Inadequate uterine receptivity is responsible for approximately two-thirds of implantation failures. The cell adhesion molecule (CAM) such as integrins, cadherins, selectins and immunoglobulins intervene to ensure adhesiveness between the embryo and the endometrium. Some recent studies indicate th...
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Recurrent implantation failure (RIF) has many definitions, but usually authors consider RIF, the failure to achieve a pregnancy fallowing 2-6 IVF cycles in which more than 10 high grade embryos were transferred to the uterus. There are a lot of causes for RIF but two main causes of that are related to embryo and endometrium. Chromosomal abnormalities, zona hardening and problems in culture medi...
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15 صفحه اولAdhesion molecules in implantation.
At implantation, trophectoderm attaches to the apical uterine luminal epithelial cell surface. Molecular anatomy studies in humans and mice, and data from experimental models have identified several adhesion molecules that could take part in this process: integrins of the alpha v family, trophinin, CD44, cad-11, the H type I and Lewis y oligosaccharides and heparan sulfate. The endometrial cell...
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ژورنال
عنوان ژورنال: Istanbul Bilim University Florence Nightingale Journal of Medicine
سال: 2018
ISSN: 2149-4401,2547-9466
DOI: 10.5606/fng.btd.2018.003